Antabuse (disulfiram) is a prescription medicine that works to help the patient quit drinking by interfering with the way their body metabolizes alcohol. Antabuse can cause a number of very unpleasant effects if you have a drink after taking it. You need to be aware of the following reactions possible: flushing, dizziness, nausea, fast heartbeats, thirst, low blood pressure, and chest pain. Your doctor needs to know if you ever had the following health conditions, just to make sure taking Antabuse if safe for you and you won’t need a dose adjustment: some mental disorders, brain damage, diabetes, kidney disease, seizure disorder, thyroid disease, or liver disease. In some of these cases you may actually require a dose adjustment or additional tests. An overdose of this medicine can produce any of the following symptoms: numbness, dizziness, seizures, nausea, loss of coordination, tingling, and vomiting. If you happened to take too much of Antabuse – seek emergency medical help. If you experience tiredness, mild drowsiness, sore tongue, impotence, headache, acne, skin rash, or any other mild side effects of the kind – there is no need to worry, as these are most likely to go away on their own.